Publications

View all of Dr. Sowmya Viswanathan’s publications in PubMed, Scopus and ORCID.
ARTICLES
2023 Robb K, Viswanathan S. Proceedings of the International Society for Cell & Gene Therapy Annual Meeting Roundtable, “Failure to Launch Mesenchymal Stromal Cell Therapies: What's the Path Forward? in Cytotherapy 
  Copp G, Robb K, Viswanathan S Culture-expanded mesenchymal stromal cells and knee osteoarthritis – does it work? A review of clinical evidence, mechanism of action and roadmap for next steps in Cellular & Molecular Immunology
  Chinnadurai, R, Viswanathan, S, Guido, M Next Generation Mesenchymal Stromal Cell Therapy Manufacturing, Potency and Mechanism of Action Analysis in Frontiers in Immunology (Editorial for Special Research Issue)
2022 Robb K et al.

Putative critical quality attribute matrix identifies mesenchymal stromal cells with potent immunomodulatory and angiogenic “fitness” ranges in response to culture process parameters in Frontiers in Immunology

  Weiss, DJ, Filiano, A, Galipeau J, et al. An ISCT MSC Committee Editorial on overcoming limitations in clinical trials of mesenchymal stromal cell therapy for COVID-19: Time for a global registry in Cytotherapy
  Banh L, Cheung KK, Chan MWY, et al. Advances in Organ-on-a-Chip Systems for Modelling Joint Tissue and Osteoarthritic Diseases in Osteoarthritis and Cartilage
  Sartore L, Pasini C, Pandini S, et al. Hybrid core-shell polymer scaffold for bone tissue regeneration in International Journal of Molecular Sciences
  Viswanathan S, Moreyra PA, Berenbaum F, et al. How the COVID-19 pandemic has affected rheumatology research in Nature Reviews Rheumatology
  Chan MWY, Gómez-Aristizábal A, Mahomed N, et al. A tool for evaluating novel osteoarthritis therapies using multivariate analyses of human cartilage-synovium explant co-culture in Osteoarthritis and Cartilage
2021 Viswanathan S, Ciccocioppo R, Galipeau J, et al. Consensus ICCBBA-ISCT statement on standard nomenclature abbreviations for the tissue of origin of Mesenchymal Stromal Cells in Cytotherapy
  Lin-Gibson S, Lin NJ, Jackson S, et al. Standards efforts and landscape for rapid microbial testing methodologies in regenerative medicine in Cytotherapy
  Galipeau J, Krampera M, Leblanc K, et al. Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition in Cytotherapy
  Abji F, Rasti M, Gómez-Aristizábal A, et al. Proteinase-mediated Macrophage Signalling in Psoriatic Arthritis in Frontiers in Immunology
2020 Khoury M, Rocco PRM, Phinney DG, et al. Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential in Cytotherapy
  Rockel JS, Rabani R, Viswanathan S. Anti-fibrotic mechanisms of exogenously-expanded mesenchymal stromal cells for fibrotic diseases in Seminars in Cell & Developmental Biology
2019 Viswanathan S, Shi Y, Galipeau J, et al. Mesenchymal stem versus stromal cells: International Society for Cell & Gene Therapy (ISCT®) Mesenchymal Stromal Cell committee position statement on nomenclature in Cytotherapy
  Chisholm J, Ruff C, Viswanathan S. Current state of Health Canada regulation for cellular and gene therapy products: potential cures on the horizon in Cytotherapy
  Chahal J, Gómez-Aristizábal A, Shestopaloff K, et al. Bone Marrow Mesenchymal Stromal Cell Treatment in Patients with Osteoarthritis Results in Overall Improvement in Pain and Symptoms and Reduces Synovial Inflammation in Stem Cells Translational Medicine. This article was ranked #1 most-read paper of 2019 by Stem Cells Translational Medicine.
  Bubela T, Boch R, Viswanathan S. Recommendations for Regulating the Environmental Risk of Shedding for Gene Therapy and Oncolytic Viruses in Canada in Frontiers in Medicine (Lausanne)
  Hamilton AM, Cheung WY, Gómez-Aristizábal A, et al. Iron nanoparticle-labeled murine mesenchymal stromal cells in an osteoarthritic model persists and suggests anti-inflammatory mechanism of action in PLoS One
  Robb KP, Fitzgerald JC, Barry F, Viswanathan S. Mesenchymal stromal cell therapy: progress in manufacturing and assessments of potency in Cytotherapy
  Chan MWY, Viswanathan S. Recent progress on developing exogenous monocyte/macrophage-based therapies for inflammatory and degenerative diseases in Cytotherapy
  Gómez-Aristizábal A, Gandhi R, Mahomed NN, et al. Synovial fluid monocyte/macrophage subsets and their correlation to patient-reported outcomes in osteoarthritic patients: a cohort study in Arthritis Research and Therapy
2018 Fink C, Gaudet JM, Fox MS, et al. 19F-perfluorocarbon-labeled human peripheral blood mononuclear cells can be detected in vivo using clinical MRI parameters in a therapeutic cell setting in Scientific Reports
2017 Chisholm J, von Tigerstrom B, Bedford P, et al. Workshop to address gaps in regulation of minimally manipulated autologous cell therapies for homologous use in Canada in Cytotherapy
  Williams BA, Law AD, Routy B, et al. A phase I trial of NK-92 cells for refractory hematological malignancies relapsing after autologous hematopoietic cell transplantation shows safety and evidence of efficacy in Oncotarget
  Yannarelli G, Pacienza N, Montanari S, et al.  OCT4 expression mediates partial cardiomyocyte reprogramming of mesenchymal stromal cells in PLoS One
  Chisholm J, Bhatt S, Chaboureau A, Viswanathan S. Strategy for an abbreviated in-house qualification of a commercially available Rapid Microbiology Method (RMM) for canadian regulatory approval in Cytotherapy
  Gómez-Aristizábal A, Sharma A, Bakooshli MA, et al. Stage-specific differences in secretory profile of mesenchymal stromal cells (MSCs) subjected to early- vs late-stage OA synovial fluid in Osteoarthritis Cartilage
  Rashedi I, Gómez-Aristizábal A, Wang XH, et al. TLR3 or TLR4 Activation Enhances Mesenchymal Stromal Cell-Mediated Treg Induction via Notch Signaling in Stem Cells
2016 Juneja SC, Viswanathan S, Ganguly M, Veillette C.  A Simplified Method for the Aspiration of Bone Marrow from Patients Undergoing Hip and Knee Joint Replacement for Isolating Mesenchymal Stem Cells and In Vitro Chondrogenesis in Bone Marrow Research
  Gómez-Aristizábal A, Kim KP, Viswanathan S. A Systematic Study of the Effect of Different Molecular Weights of Hyaluronic Acid on Mesenchymal Stromal Cell-Mediated Immunomodulation in PLoS One
  Galipeau J, Krampera M, Barrett J, et al. International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials in Cytotherapy
2015 Montanari S, Dayan V, Yannarelli G, et al. Mesenchymal stromal cells improve cardiac function and left ventricular remodeling in a heart transplantation model in The Journal of Heart and Lung Transplantation
  Bubela T, McCabe C, Archibald P, et al. Bringing regenerative medicines to the clinic: the future for regulation and reimbursement in Regenerative Medicine
  Viswanathan S, Bubela T. Current practices and reform proposals for the regulation of advanced medicinal products in Canada in Regenerative Medicine

BOOKS
2017 Mesenchymal Stromal Cells

BOOK CHAPTERS
2015 Osteoarthritis
2013 Mesenchymal Stromal Cells
2013 New Perspectives in Regeneration